When Your Roller Coaster Won’t Slow Down and You Know You Can’t Trust Anyone Anymore

Of the many biochemical imbalances seen at Health Recovery Center, abnormally high histamine levels (histadelia) is certainly one of the more frustrating. Typically histadelic clients sweep into my office in high arousal about life in general, showing compulsive/ obsessive tendencies, and expecting an instant fix.

  • Often they’re seriously depressed
  • They may have attempted suicide or have a family history of suicides
  • They don’t sleep much or well
  • They cry at the drop of a hat
  • They are often terribly impulsive

Histadelic’s who have tried drugs tend to prefer heroin or other narcotics, and sometimes alcohol. These chemicals block histamine and improve their symptoms temporarily. Many have successful careers, fueled by their remarkable drive and energy, but internally they are crumbling from continual tension and depression.

Gradually I began to recognize a pattern repeating itself with each new histadelic client: Enthusiasm ran unrealistically high the first few days, but there was no staying power ... often before the first week was over, histadelics impulsively lost interest, abandoned their program to return to drugs or some other new-found project.

I recognized similar characteristics of these dropouts. Their profiles fit perfectly with Dr. Carl Pfeiffer’s description of high-histamine persons, and I realized we must intervene immediately if we hoped to hold their attention. We began using Dr. Pfeiffer’s formula for lowering histamine.

The natural histamine blockers turned the tide. They make enough difference early on to thwart the impulsiveness of these people. Now we rarely lose histadelic clients, and once they are well, they are some of the most vocal supporters of these methods.

What Histamine Does

I’ll bet your concept of histamine is of some vague body fluid that gets released in allergic reactions and causes sneezing, mucous, and swelling. You may not realize the serious mischief this chemical can do. Inside the brain it has an important role, in all sorts of reactions.

If histamine brain levels go too low:

  • We become paranoid and suspicious
  • Our pain sensitivity goes down
  • Our sexual libido declines
  • Our ears may ring
  • We may see or hear things abnormally
  • We may devise grandiose plans, but never find the energy to carry them out

When brain histamine levels go too high, other frightening symptoms occur:

  • A tendency towards hyperactivity
  • Obsessive behavior takes over
  • Obsessiveness about sex
  • Black depression
  • Abnormal fears
  • Compulsive rituals It causes our tears to flow
  • Cry easily
  • We may even think about suicide, often

Many high-powered, energetic politicians and public figures show the high histamine combination of obsessive drive and high sexual libido. Without their abnormally high histamine, they would lack the stamina to fuel their careers so intensely.

Unfortunately, their high sex drive can sometimes bring their undoing, despite being splendid statesmen in every other way. Once we see ourselves and others in the light of the chemistry we are dealt, we tend to become more understanding about the corresponding behaviors.

Science Finds a New Brain Regulation

The consequences of histamine imbalance in the brain was discovered at the New Jersey Psychiatric Institute in 1966 where Dr. Carl Pfeiffer and his colleagues devised a method for accurately assaying tissue histamine content, followed by the discovery that the blood (and therefore presumably the brain) of most schizophrenics contained abnormal levels of histamine.

They watched seventy-two chronic schizophrenics with abnormally low histamine gradually improve as levels were restored to normal. Another group of their patients showed highly elevated histamine. These patients experienced a marked reduction of symptoms as their high histamine levels were brought down to the normal range.

It is now well established that over two-thirds of schizophrenics have abnormal histamine readings. However, many of the people we treat at Health Recovery Center also have marked histamine abnormalities, and almost all are NOT schizophrenic.

How Histamine Works in the Brain

In the hypothalamus, histamine stimulates the release of the important neurotransmitters serotonin, dopamine and norepinephrine. Another role of brain histamine is to counterbalance dopamine in that area of the brain that filters sensory information coming into your brain.

With too little histamine, dopamine levels are elevated. The result of too low histamine can be thought disorders or even hallucinations that feel like your mind is playing tricks on you.

Other psychiatric symptoms develop when too MUCH histamine heightens and distorts the release of these key neurotransmitters serotonin, dopamine and norepinephrine. Abnormally high, histamine will cause over stimulation, aggressiveness, compulsivity, and a racing brain (among other symptoms.)


Histamine and Prostaglandin E1 Appear Linked

Histamine levels and PGE1 levels (made from Omega 6 essential fatty acids) have recently been shown to move in the same direction. The same natural substances raise and lower both histamine and PGE1 in the brain and body. Their interrelationship is significant when setting out to repair the many psychological and psychiatric problems abnormal levels trigger.